KMID : 1100220030020020108
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Dementia and Neurocognitive Disorders 2003 Volume.2 No. 2 p.108 ~ p.114
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Treatment of Mild Cognitive Impairment
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Bae Hee-Joon
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Abstract
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Mild cognitive impairment (MCI) is a recently described syndrome that is currently thought of as a transition phase between healthy cognitive aging and dementia. At the moment, many treatment strategies for Alzheimer¡¯s disease were extrapolated to interventional strategies in MCI. Most investigators believe that by the time the clinical diagnosis of Alzheimer¡¯s disease is made, sufficient neuronal damage has taken place in the brain to make reversal of the condition unlikely. Therefore, it is a more effective strategy to treat patients in preclinical stage of Alzheimer¡¯s disease, such as MCI, than to treat in its advanced stage. This article reviews currently available symptomatic treatments and visionary treatments for Alzheimer¡¯s disease and MCI. A number of clinical trials for MCI, which are ongoing at now, are discussed.
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KEYWORD
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Mild cognitive impairment, Alzheimer¡¯s disease, Treatment
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